HEART DISEASE

This study tests whether combining healthy food access, nutrition education, and personalized coaching can help families improve heart health. Participants include one parent with a BMI over 30 and their child aged 6–11, both on Medicaid. Families may receive groceries, cooking c…

This study tests a temporary heart pump called the Supira System in 45 people with heart failure and severe coronary artery disease who need high-risk angioplasty. The pump is inserted through a leg artery to help the heart pump blood during and after the procedure. Researchers w…

This study tests a program that uses an AI chatbot, health coach, and home monitoring devices to help 300 adults with heart disease, diabetes, or kidney disease manage their conditions. The goal is to see if this approach reduces hospital visits, complications, and deaths over 6 …

This study tests a drug called orticumab in 240 people who had a heart attack and still have high inflammation in their heart arteries. Participants receive either orticumab or a placebo for 24 weeks. The main goal is to see if orticumab lowers inflammation measured by a special …

This study tests whether providing healthy frozen meals, produce boxes, and nutrition counseling helps adults in Anson County eat better compared to those who only get physical activity coaching. About 120 participants with or at risk for chronic diseases like obesity, diabetes, …

This study is testing a chest-patch that uses light to measure blood pressure without a traditional arm cuff. Researchers will compare its readings over 24 hours to the standard cuff-based method in 600 adults with or without high blood pressure. The goal is to see if the patch i…

This study is testing whether combining AI-powered electrocardiograms (ECGs) with focused heart ultrasound can effectively screen for heart disease in everyday community settings. Researchers at Mayo Clinic plan to enroll 19,300 people, including teens, adults, and pregnant women…

This study tests whether ultrasound contrast agents (microbubbles) can estimate pressure inside the heart, potentially replacing invasive catheters. Ten adults with suspected heart disease will receive a standard ultrasound with contrast while also having a catheter for compariso…

This study aims to increase physical activity and fitness among 290 Latino families living near the U.S.-Mexico border. Parents and children aged 6-11 will take part in a 12-month program at community centers, with progressive sports skills and behavioral coaching. The goal is to…

This study looks at how your genes and your environment—like what you eat, breathe, and experience—work together to influence common diseases such as diabetes, heart disease, and asthma. Researchers are collecting health questionnaires, genetic data, and other information from 25…

This study looks at whether training doctors on quickly starting and adjusting heart failure medications (called GDMT) during a hospital stay leads to better treatment after discharge. About 438 adults with heart failure and reduced ejection fraction will be observed across multi…

This study looks at whether a special nursing care model helps people with long-term health conditions like diabetes, heart disease, or Parkinson's work better with their advanced practice nurse. About 420 adults will take part. The goal is to see if this approach improves how pa…

This study tests whether a smartphone app (DigitHeart-2) can accurately predict heart structure and function from a simple ECG picture. About 478 adults who need an echocardiogram will have their ECG photo analyzed by the app, and the results will be compared to the standard ultr…

This study is testing a tool called Transit-Time Flow Measurement (TTFM) that uses sound waves during heart bypass surgery to check blood flow through the new blood vessels. The goal is to see if using this tool helps the grafts stay open longer. About 1242 adults having their fi…

This study follows 750 people with sickle cell disease to see how curative therapies affect the heart, lungs, and kidneys over time. Researchers will compare those who received a stem cell transplant with those on standard treatment. The goal is to understand whether curative the…

This study tracks 150 adults in cardiac rehab to see if men and women differ in how much they move during and up to 6 months after the program. Participants wear activity trackers and complete fitness tests at three visits over 10 months. The goal is to understand barriers to sta…

This study is building a registry of genetic and health information from 3,000 people with conditions like diabetes, high cholesterol, cancer, and heart disease. The goal is to help doctors choose the safest and most effective medications based on a person's genetic makeup. Parti…