New Catheter-Based valve replacement offers hope for High-Risk heart patients

NCT ID NCT07130994

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new device called the SATURN TS TMVR System, which is implanted through a catheter to replace the mitral valve in people with severe mitral regurgitation. Up to 15 patients who are too high-risk for open-heart surgery will be enrolled. The goal is to see if the device can be safely implanted and reduce the backward flow of blood in the heart.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SATURN TS TMVR System (a device implanted via catheter to replace the mitral valve)

What this could lead to

If successful, this could offer a less invasive treatment option for people with severe mitral regurgitation who are too high-risk for open-heart surgery.

What could go wrong

This is a very early feasibility study with only 15 participants, so results may not apply widely. The procedure carries risks like stroke, heart damage, or need for reintervention.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart disorder mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

    Contact Email: •••••@•••••

    Contact

  • Columbia University Irving Medical Center/New York Presbyterian Hospital

    New York, New York, 10032, United States

    Contact

    Contact Email: •••••@•••••

  • Los Robles Regional Medical Center

    Thousand Oaks, California, 91360, United States

    Contact Email: •••••@•••••

    Contact

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact

  • UC Davis Health

    Sacramento, California, 95817, United States

    Contact

    Contact Email: •••••@•••••