MITRAL REGURGITATION

This study is testing a new device called the Cephea Mitral Valve System for people with a leaky or narrowed mitral valve in their heart. The goal is to see if this less invasive procedure, done through a catheter, is safe and can effectively reduce the severity of the valve prob…

This study is testing a new device called the HighLife valve for people with a severely leaking mitral heart valve who are too high-risk for traditional open-heart surgery. Doctors will implant the new valve using a thin tube (catheter) inserted through a vein, aiming to fix the …

This study is testing a less invasive procedure to replace a severely calcified mitral heart valve in patients who are too high-risk for standard open-heart surgery. Doctors will implant a new valve using a catheter inserted through a vein, aiming to improve symptoms and reduce h…

This study is testing a new device called the SAPIEN M3 System to replace a leaky mitral heart valve without major open-heart surgery. It's for people with severe symptoms from their leaky valve who are not good candidates for standard surgical or other catheter-based treatments.…

This study aims to see if surgery to repair a leaky, floppy mitral heart valve can reduce dangerous irregular heartbeats and heart scarring in patients who have both conditions. Researchers will follow 90 patients needing this standard surgery, checking their heart rhythms and pe…

This study is testing a new device called the Cephea Mitral Valve System. It aims to treat people with a leaky or narrowed heart valve using a less invasive catheter procedure instead of open-heart surgery. The main goals are to see if the procedure is safe and if it successfully…

This study is testing a new device called the Tioga TMVR System that replaces leaky mitral heart valves through a small tube inserted in the leg, avoiding open-heart surgery. The trial will enroll 30 patients with severe, symptomatic mitral regurgitation who are not ideal candida…

This study is testing a new, step-by-step treatment plan for people with heart failure and a specific leaky heart valve. It aims to see if this plan helps doctors better identify which patients are most likely to benefit from a minimally invasive procedure called MitraClip. The s…

This study aims to find the safest blood thinner approach for patients who have undergone a minimally invasive heart valve repair procedure. Researchers will compare different medication strategies in over 1,000 patients to determine which approach best balances the risk of bleed…

This trial is testing a new device called the Intrepid TMVR System for people with a severely leaking heart valve (mitral regurgitation) who are too high-risk for standard valve repair or replacement surgery. Doctors will implant the new valve using a thin tube (catheter) inserte…

This study aims to find the best blood thinner strategy for patients who have undergone a minimally invasive heart valve repair and also need long-term blood thinners. Researchers will compare different approaches to balance the risks of dangerous bleeding against the risks of st…

This early-stage study is testing a new device called the ReValve System to replace leaky mitral valves in the heart. The trial will enroll 20 adults with severe mitral regurgitation who are experiencing symptoms like shortness of breath and fatigue. Researchers will assess wheth…

This study is testing a new device called the CardioMech MVRS to see if it is safe and works well for repairing a leaky mitral heart valve. It is for people with a significant leak who are at intermediate or high risk for traditional open-heart surgery. The goal is to control the…

This study aims to understand how heart valve disease affects men and women differently using advanced heart scans. Researchers will analyze detailed heart images from 200 adults with moderate to severe valve problems to identify patterns that might explain why women often have w…

This study is collecting information from 1,000 people with symptomatic mitral valve disease, which involves a leaky or narrowed heart valve. The goal is to track how patients do after receiving a minimally invasive valve replacement procedure. The data will help doctors better u…