Heart valve repair devices under 5-Year safety spotlight
NCT ID NCT04761120
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 550 people who receive Abbott annuloplasty rings or bands during surgery to fix leaky mitral or tricuspid heart valves. Researchers will track survival, need for repeat surgery, and symptom improvement for five years. The goal is to confirm the devices work well in real-world use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Annuloplasty rings and bands (medical devices implanted during heart valve repair surgery)
- What this could lead to
- If successful, this study will confirm that these devices are safe and effective for repairing leaky heart valves, helping patients breathe easier and live longer.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be influenced by other factors. The devices are already on the market, so no new breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MITRAL REGURGITATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
CHU de Besançon - Jean Minjoz
RECRUITINGBesançon, Bourgogne-Franche-Comté, 25000, France
Contact
-
Catharina Ziekenhuis
RECRUITINGEindhoven, North Brabant, 5623 EJ, Netherlands
Contact
-
Duke University Hospital
WITHDRAWNDurham, North Carolina, 27710, United States
-
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITINGMilan, Lombard, 20157, Italy
Contact
-
Herzchirurgische Abteilung Klinikum Passau
RECRUITINGPassau, Bavaria, 94032, Germany
Contact
-
Herzzentrum Dresden, Universitätsklinik an der Technischen Universität Dresden
RECRUITINGDresden, Saxony, 01307, Germany
Contact
-
Herzzentrum-Bremen Klinikum Links der Weser
RECRUITINGBremen, Free Hanseatic City of Bremen, 28211, Germany
Contact
-
Hopital Cardiovasculaire et Pneumologique Louis Pradel
RECRUITINGLyon, Auvergne-Rhône-Alpes, 69500, France
Contact
-
Hospital Alvaro Cunqueiro
RECRUITINGVigo, Pontevedra, 36312, Spain
Contact
-
Ospedale Luigi Sacco
WITHDRAWNMilan, Milan, 20157, Italy
-
Ospedale San Raffaele - Cardiac
RECRUITINGMilan, Lombardy, 1350, Italy
Contact
-
Ospedale Umberto I
RECRUITINGTurin, Piedmont, 10128, Italy
Contact
-
Policlinico S.Orsola-Malpighi
RECRUITINGBologna, Bologna, 40138, Italy
Contact
-
Tartu University Hospital
RECRUITINGTartu, 50406, Estonia
Contact
-
University of Wisconsin Hospital and Clinics
WITHDRAWNMadison, Wisconsin, 53792, United States
-
Universitätsklinikum Jena
RECRUITINGJena, Thuringia, 07740, Germany
Contact
-
Universitätsklinikum Würzburg
COMPLETEDWürzburg, Bavaria, 97080, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A new Catheter-Based valve could fix a leaky heart valve without surgery
- New heart valve device could spare High-Risk patients from Open-Heart surgery
- First-in-Human trial aims to offer new hope for patients with leaky heart valves who Can't have surgery
- Prepping the body before heart surgery: could exercise shorten hospital stays?
- Wireless sensor could help doctors Fine-Tune heart failure treatment in real time
- Tiny device could fix leaky heart valves without cutting chest open