TRICUSPID REGURGITATION

This early study tests a new device called the Trisol system for people with a leaky tricuspid heart valve (tricuspid regurgitation). The goal is to see if the device is safe and can reduce the leak. About 30 participants with moderate or worse symptoms will be enrolled. The devi…

This study looks at whether treating severe tricuspid valve leakage can improve kidney function, reduce swelling, and boost physical activity in older adults. About 100 participants will receive a valve repair procedure and be monitored for changes in kidney health, walking abili…

This study tests a new device called the Cardiovalve system to replace a leaky tricuspid valve in the heart. It includes 150 people with severe tricuspid regurgitation who are at high risk for open-heart surgery. The goal is to see if the device safely reduces the leak and improv…

This early study tests a new device called the Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System in 15 people aged 60-90 with severe tricuspid regurgitation (a leaky heart valve). The goal is to see if the device can be safely implanted and reduce the valve leakage.…

This is an early study to see if a new device called the DUO System is safe and works for people with a severely leaky tricuspid heart valve. Doctors will place the device using a catheter through a blood vessel, avoiding open-heart surgery. The study will follow 15 patients for …

This study is testing a new device called the VDyne System to replace the tricuspid valve in people with severe tricuspid regurgitation (a leaky heart valve). About 120 adults who have not improved with standard heart failure medications will receive the device. The goal is to se…

This study tests a new device called Pivot Extend for people with severe tricuspid regurgitation, a leaky heart valve. The device is placed using a thin tube through a blood vessel, avoiding open-heart surgery. The study includes 10 adults who are at high risk for surgery. The go…

This study tests a new device that replaces a leaky tricuspid heart valve using a tube inserted through a leg vein, avoiding open-heart surgery. It includes 150 people with severe valve leakage who are still having symptoms despite medication. The goal is to see if the device is …

This study tests a device called the Edwards PASCAL system to repair a leaky tricuspid heart valve without open-heart surgery. About 1,270 people with severe symptoms will be randomly assigned to get the device plus standard medical care, or standard care alone. The goal is to se…

This study tests a new device called the VDyne System to replace the tricuspid valve in people with severe leakage. The goal is to see if it safely reduces symptoms and improves daily life. About 30 adults with severe tricuspid regurgitation will be enrolled. The approach is a mi…

This study looks at how well the TriClip system works and how safe it is for people in Japan with a leaky heart valve (tricuspid regurgitation). The device is already approved for use, and this study will follow 250 patients to confirm it controls the leak and has few complicatio…

This study tests a new device called the Cardiovalve TR system to replace a leaky tricuspid valve in the heart. About 100 people with moderate to severe leakage and symptoms like shortness of breath will get the implant. The goal is to see if the device is safe and can reduce the…

This study follows 200 adults who have had or will have a procedure to fix a leaky or narrowed right heart valve. Researchers will check participants' health through blood tests, heart ultrasounds, and medical records for two months after the procedure. The goal is to learn which…

This study is a global registry that will track 800 people with a leaky tricuspid heart valve (tricuspid regurgitation) who undergo a new, less invasive valve replacement procedure called TTVR. The goal is to learn how safe and effective the procedure is by monitoring complicatio…