New heart valve fix could spare High-Risk patients from major surgery

NCT ID NCT07172477

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new device called the Pivot Extend in 10 adults with severe tricuspid regurgitation (a leaky heart valve) who are too high-risk for surgery. The device is threaded through a vein in the leg to the heart, where it helps the valve flaps close tightly. The goal is to see if it is safe and can reduce the backward flow of blood, easing symptoms like shortness of breath and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pivot Extend device (a catheter-delivered implant to help the tricuspid valve close)

What this could lead to

If it works, this could offer a less risky option for people with severe tricuspid regurgitation who cannot have open-heart surgery.

What could go wrong

This is a very early feasibility study with only 10 participants, so results may not apply to everyone. The device could fail to reduce leakage or cause serious complications like stroke or heart attack.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Macquarie University

    RECRUITING

    Macquarie Park, New South Wales, 2109, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••