New heart valve device tested in canada for severe leaky valve

NCT ID NCT07171060

Recruiting now Disease control Sponsor: Laplace Interventional, Inc Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This early study tests a new device called the Laplace TTVR System, which is designed to replace the tricuspid valve without open-heart surgery. It involves 15 people aged 60-90 with severe tricuspid regurgitation that continues despite medication. The main goal is to see if the device can be safely implanted and works as intended.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Laplace TTVR System (a device for replacing the tricuspid valve without open-heart surgery)
What this could lead to: If it works, this could offer a less invasive treatment option for people with severe tricuspid regurgitation who are not helped by medication alone.
What could go wrong: This is a very early, small study (15 people) focused on safety and feasibility. The device may not work as expected, and there are risks from the procedure itself, such as complications from valve implantation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRICUSPID REGURGITATION

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

St. Michael's Hospital
RECRUITING

Toronto, Ontario, M5B 1W8, Canada
Sunnybrook Research Institute
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
University of Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada

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