New heart valve device offers hope for patients with leaky tricuspid valve

NCT ID NCT05848284

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called the VDyne System to replace the tricuspid valve in people with severe tricuspid regurgitation (a leaky heart valve). The goal is to see if the device is safe and can improve symptoms, exercise ability, and quality of life. About 30 adults with severe symptoms will be enrolled and followed for one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

tricuspid valve disorder tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ascension St. Thomas

    RECRUITING

    Nashville, Tennessee, 37205, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Columbia University Medical Center/NYPH

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henry Ford Hospital

    RECRUITING

    Detriot, Michigan, 48208, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic - Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Minneapolis Heart Institute Foundation

    RECRUITING

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science Unversity

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Québec-Université Laval (IUCPQ-ULaval)

    RECRUITING

    Québec, Quebec, G1V 4G5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Christ Hospital

    RECRUITING

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact