New heart valve device aims to fix leaky tricuspid without open surgery
NCT ID NCT05913908
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study is testing a new device called the DUO System, which is placed through a catheter to reduce leakage in the tricuspid valve. The study will include 15 people with severe tricuspid regurgitation who still have symptoms despite medical therapy. The main goal is to see if the device is safe and works properly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DUO Transcatheter Tricuspid Coaptation Valve System (a device implanted via catheter to reduce tricuspid valve leakage)
What this could lead to
If successful, this could offer a less invasive treatment option for people with severe tricuspid regurgitation who are not candidates for open-heart surgery.
What could go wrong
This is a very early feasibility study with only 15 participants, so results may not apply to everyone. The device could cause serious complications like bleeding, stroke, or heart damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Allina Health Minneapolis Heart Institute Foundation
RECRUITINGMinneapolis, Minnesota, 55407, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ascension Via Christi Research
RECRUITINGWichita, Kansas, 67214, United States
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Contact Email: •••••@•••••
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Columbia University Medical Center/NYPH
RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
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Dignity Health St. Joseph's Hospital & Medical Center
RECRUITINGPhoenix, Arizona, 85013, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Intermountain Health
RECRUITINGSalt Lake City, Utah, 84111, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Los Robles Hospital & Medical Center
RECRUITINGThousand Oaks, California, 91360, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medical University of Silesia
RECRUITINGKatowice, 40-635, Poland
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Narodowym Instytutem Kardiologii Stefana Kardynała Wyszyńskiego - Państwowym Instytutem Badawczym
RECRUITINGWarsaw, Warsaw, 04-628, Poland
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Contact Phone: •••-•••-••••
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact Email: •••••@•••••
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OhioHealth Research Institute
RECRUITINGColumbus, Ohio, 43214, United States
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Piedmont Heart Institute
RECRUITINGAtlanta, Georgia, 30309, United States
Contact Email: •••••@•••••
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San Antonio Methodist
ENROLLING_BY_INVITATIONSan Antonio, Texas, 78229, United States
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UPMC Pinnacle Harrisburg
RECRUITINGHarrisburg, Pennsylvania, 17050, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington
RECRUITINGSeattle, Washington, 98195, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Uniwersytetem Medycznym im. Karola Marcinkowskiego w Poznaniu
RECRUITINGPoznan, Poznan, 60-355, Poland
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••