Can the heart repair its own valve? a new surgical approach

NCT ID NCT07761273

ENROLLING_BY_INVITATION Disease control Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests a new surgical technique for people with tricuspid valve disease, where the valve on the right side of the heart is damaged. Instead of replacing the valve with an artificial one, surgeons will use a piece of the heart's own chamber, called the right atrial appendage, to rebuild it. The study will compare this approach to standard valve replacement, looking at safety, survival, and how well the new valve works over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Surgical procedure using the right atrial appendage to reconstruct the tricuspid valve
What this could lead to: If successful, this approach could offer a safer, more durable alternative to standard tricuspid valve replacement, potentially reducing complications and improving heart function.
What could go wrong: This is a small, early-stage trial, so results may not apply broadly. Surgery carries risks like bleeding, infection, or the new valve not working well, and long-term outcomes are unknown.

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Conditions

The condition(s) this trial relates to.

tricuspid valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRICUSPID VALVE DISEASE

Contacts and locations

Locations

Amr El Sayed Tawfek

Zagazig, Sharqia Province, 44519, Egypt
Amr Tawfek

Zagazig, Sharqia Province, 44519, Egypt
cardiothorathic surgery department -faculty of medecine-zagazig univeristy- Egypt

Zagazig, Sharqia Province, 44519, Egypt

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