New valve implant offers hope for rare heart condition

NCT ID NCT05064514

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a custom-made artificial heart valve, called TRICENTO, in 15 people with carcinoid heart disease who have severe leakage of the tricuspid valve and cannot have surgery. The valve is delivered through a catheter, avoiding open-heart surgery. The goal is to see if it reduces valve leakage and improves symptoms and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TRICENTO valved stent graft (a custom-made artificial heart valve delivered through a catheter)

What this could lead to

If it works, this could offer a less invasive treatment option for people with carcinoid heart disease who have severe valve leakage and cannot undergo open-heart surgery.

What could go wrong

This is a very early, small study with only 15 participants, so results may not apply to everyone. The procedure carries risks like any heart implant, and the valve may not work as intended or could cause complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carcinoid heart disease carcinoid syndrome carcinoid tumor serotonin syndrome tricuspid valve disorder tricuspid valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barts Health NHS Trust

    London, England, E1 1BB, United Kingdom