Worldwide registry aims to unlock secrets of tricuspid valve replacement
NCT ID NCT06033274
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This global registry will follow 800 patients receiving a new, less-invasive tricuspid valve replacement (TTVR) for leaky heart valves. Researchers aim to track complications like pacemaker needs and how well the valve works over time. The study does not test a new drug but gathers real-world data to guide future care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter Tricuspid Valve Replacement (a device procedure to replace the tricuspid valve without open-heart surgery)
What this could lead to
If successful, this registry could provide crucial data to improve the safety and effectiveness of a less invasive valve replacement for people with severe tricuspid regurgitation.
What could go wrong
This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be limited by differences in patient care across centers.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Arizona Heart Hospital (Biltmore Cardiology)
RECRUITINGPhoenix, Arizona, 85016, United States
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Cardiovascular Center (CVC) Frankfurt, Division of Cardiology
RECRUITINGFrankfurt, 60389, Germany
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Centre Hospitalier Universitaire de Lille
RECRUITINGLille, 59000, France
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Centro Cardiologico Monzino IRCCS
RECRUITINGMilan, 20138, Italy
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Chu De Bordeaux - Haut-Lévêque Hospital
RECRUITINGBordeaux, Pessac, 33600, France
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Clinique Pasteur Toulouse
RECRUITINGToulouse, 31300, France
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
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Heart Center Cologne, University of Cologne
RECRUITINGCologne, 50924, Germany
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Heart and Diabetes Centre, North Rhine-Westphalia (NRW), Ruhr-University
RECRUITINGBad Oeynhausen, 32545, Germany
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Medical Clinic and Polyclinic, University Hospital of Munich (LMU Klinikum)
RECRUITINGMunich, 80333, Germany
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Montefiore Medical Center
RECRUITINGThe Bronx, New York, 10461, United States
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Oregon Health & Science University
ENROLLING_BY_INVITATIONPortland, Oregon, 97239, United States
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Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada
RECRUITINGQuébec, Quebec, G1V 4G5, Canada
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Rigshospitalet, Copenhagen University Hospital
RECRUITINGCopenhagen, 2100, Denmark
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San Raffaele University Hospital
RECRUITINGMilan, 20132, Italy
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St Michael's Hospital, University of Toronto
RECRUITINGToronto, Ontario, M5B 1W8, Canada
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St. Paul's Hospital
RECRUITINGVancouver, British Columbia, V6Z 1Y6, Canada
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University Heart Center, Schleswig-Holstein University
RECRUITINGLübeck, D-23538, Germany
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University Heart and Vascular Center, Department of Cardiology
RECRUITINGHamburg, 20251, Germany
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University Hospital Alvaro Cunqueiro (CHUVI)
RECRUITINGVigo, Pontevedra, 36312, Spain
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