MITRAL REGURGITATION
Clinical trials for MITRAL REGURGITATION explained in plain language.
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New heart valve device shows promise for severe leaky valve patients
Disease control OngoingThis study tested a new device called the Tendyne Transcatheter Mitral Valve System to treat people with a severe leaky heart valve (mitral regurgitation). About 103 participants received either the Tendyne device or another approved device. The goal was to see if the new valve i…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 17, 2026 03:14 UTC
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New heart valve procedure aimed at High-Risk patients, but study never started
Disease control TerminatedThis study planned to test a new device called the Cardiovalve, which is placed through a leg vein to replace a leaky mitral heart valve without open-chest surgery. It was designed for people with severe mitral regurgitation who were too high-risk for traditional surgery. However…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 17, 2026 03:14 UTC
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Heart valve surgery gets a smarter Decision-Making tool
Disease control OngoingThis study looks at people with a leaky heart valve caused by heart disease. Currently, surgeons choose between repairing or replacing the valve based on their own experience. This trial tests whether using a specific set of measurements (an algorithm) to guide that choice leads …
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated May 17, 2026 03:12 UTC
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New Catheter-Based valve offers hope for High-Risk heart patients
Disease control OngoingThis study tests a new device that fixes a severe leaky heart valve (mitral regurgitation) without open-heart surgery. It is for 30 people who are too high-risk for traditional surgery. The device is threaded through a vein in the leg to the heart, and the study will check if it …
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 17, 2026 03:01 UTC
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New clip procedure could offer High-Risk heart patients a safer alternative to surgery
Disease control OngoingThis study tests whether a minimally invasive clip repair (MitraClip) is as effective as open-heart surgery for people with severe mitral regurgitation who are at high risk for surgery. About 330 participants will be randomly assigned to one of the two treatments and followed for…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Nantes University Hospital • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New heart valve clip shows promise in major trial
Disease control OngoingThis study tests a new device called PASCAL against an existing one, MitraClip, to fix leaky mitral valves without open-heart surgery. About 1,200 people with severe mitral regurgitation who are too high-risk for surgery took part. The goal is to see if PASCAL is as safe and effe…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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New heart valve without open surgery: hope for High-Risk patients
Disease control ENROLLING_BY_INVITATIONThis study tests a new replacement heart valve for people with severe mitral regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. The valve is delivered through a blood vessel in the leg, avoiding a large chest incision. The study will enroll 10 parti…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Cardiovalve Ltd. • Aim: Disease control
Last updated May 07, 2026 18:38 UTC
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Heart MRI may outshine ultrasound for valve surgery timing
Knowledge-focused OngoingThis study looks at 260 people with a severe leaky heart valve (mitral regurgitation) but no symptoms yet. Doctors usually use ultrasound to decide if surgery is needed. Here, half the patients' doctors also get a cardiac MRI result to see if it leads to better decisions. The goa…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Centro Cardiologico Monzino • Aim: Knowledge-focused
Last updated May 07, 2026 18:40 UTC