New clip procedure could offer High-Risk heart patients a safer alternative to surgery
NCT ID NCT03271762
First seen Jan 04, 2026 · Last updated May 13, 2026 · Updated 22 times
Summary
This study tests whether a minimally invasive clip repair (MitraClip) is as effective as open-heart surgery for people with severe mitral regurgitation who are at high risk for surgery. About 330 participants will be randomly assigned to one of the two treatments and followed for two years. The main goal is to compare rates of death, unplanned heart failure hospitalizations, and need for repeat valve procedures.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Félix Guyon
Saint-Denis, 97400, France
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CHU LYON
Lyon, France
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CHU de Rouen
Rouen, France
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Centre Cardiologique Du Nord
Saint-Denis, France
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Centre Chirurgical Marie Lannelongue
Le Plessis-Robinson, France
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Ch Annecy
Annecy, 74370, France
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Chru Brest
Brest, France
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Chru Lille
Lille, 59000, France
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Chru Tours
Tours, France
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Chu Angers
Angers, France
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Chu Bordeaux
Bordeaux, France
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Chu Grenoble
Grenoble, France
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Chu Nantes
Nantes, France
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Chu Poitiers
Poitiers, France
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Chu Rennes
Rennes, France
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Chu Saint Etienne
Saint-Etienne, 42277, France
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Clinique Du Millenaire
Montpellier, 34000, France
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Clinique Du Tonkin
Villeurbanne, 69100, France
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Clinique Pasteur
Toulouse, France
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Clinique de La Sauvegarde
Lyon, 69009, France
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Hopital Bichat
Paris, France
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Hopital Civil Strasbourg
Strasbourg, France
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Hopital Europeen Georges Pompidou
Paris, France
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Hopital Henri Mondor Aphp
Créteil, France
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Hopital La Pitie Salpetriere
Paris, France
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Hopital La Timone
Marseille, France
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Hopital Prive Le Bois Lille
Lille, 59000, France
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Hopital Rangueil
Toulouse, France
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Hopital St Joseph
Marseille, France
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Institut Hospitalier Jacques Cartier
Massy, France
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Institut Mutualiste Montsouris
Paris, France
Conditions
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