Heart valve fix without cutting chest: trial pulled before it began
NCT ID NCT03714412
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study planned to test a new device called the Cardiovalve, which is threaded through a leg vein to replace a leaky mitral valve in people too sick for open-heart surgery. The trial was withdrawn before any participants were enrolled, so no results are available. The approach aimed to offer a safer alternative for those with severe mitral regurgitation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cardiovalve transfemoral mitral valve replacement system (a device implanted via a catheter through a leg vein to replace the mitral valve)
What this could lead to
If successful, this device could offer a less invasive treatment option for people with severe mitral regurgitation who are too frail for open-heart surgery.
What could go wrong
The trial was withdrawn before any patients were enrolled, so no data exist. The device may carry risks like bleeding, valve leakage, or need for repeat procedures.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hygeia Hospital
Athens, Greece
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Silesian Center for Heart Diseases
Zabrze, 41-800, Poland