New algorithm could take guesswork out of heart valve surgery
NCT ID NCT03292497
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using a specific set of measurements (an algorithm) to decide between repairing or replacing a leaky mitral valve leads to better outcomes than letting the surgeon choose. About 110 patients with severe ischemic mitral regurgitation will be randomly assigned to either the algorithm-guided approach or standard surgeon preference. Researchers will compare changes in heart size and function over 12 months after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Treatment algorithm for mitral valve surgery
What this could lead to
If successful, this could provide a clear, evidence-based way to choose between valve repair or replacement, potentially improving heart function and reducing complications.
What could go wrong
This is a relatively small, early-stage study (110 patients) comparing two surgical approaches. The algorithm may not prove superior to surgeon preference, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Ottawa Heart Institute
Ottawa, Ontario, K1Y4W7, Canada