MITRAL REGURGITATION
Clinical trials for MITRAL REGURGITATION explained in plain language.
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Double valve fix may boost heart failure outcomes
Disease control Not yet recruitingThis study looks at whether repairing both the mitral and tricuspid heart valves at the same time is better than fixing only the mitral valve in people with severe leakage in both valves. About 404 adults with moderate-to-severe or severe valve leakage will be randomly assigned t…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Nanjing First Hospital, Nanjing Medical University • Aim: Disease control
Last updated May 17, 2026 02:04 UTC
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New MitraClip G5 registry aims to improve heart valve repair outcomes
Disease control Not yet recruitingThis registry will follow 1,000 adults with mitral regurgitation who receive the MitraClip G5, a device that repairs the heart's mitral valve without open-heart surgery. The goal is to see how well the device works and how safe it is in everyday hospital practice. No extra tests …
Matched conditions: MITRAL REGURGITATION
Sponsor: University Hospital of Cologne • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New heart valve registry aims to improve lives of patients with leaky mitral valves
Disease control Not yet recruitingThis study is a registry that will follow 150 people with severe mitral regurgitation (a leaky heart valve) who receive the HighLife transcatheter mitral valve replacement system. The goal is to see how well the device works and how safe it is in everyday medical practice. Partic…
Matched conditions: MITRAL REGURGITATION
Sponsor: HighLife SAS • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New heart valve offers hope for High-Risk patients
Disease control Not yet recruitingThis study tests a new, less invasive heart valve (SAPIEN X4) for people with mitral valve disease who are too high-risk for open-heart surgery. About 125 participants with a failing artificial valve or a damaged natural valve will receive the new valve. The goal is to see if it …
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New heart implant aims to stop leaky valve without open surgery
Disease control Not yet recruitingThis early study tests a device called the MR-ace Implant for people with moderate to severe mitral regurgitation, a condition where the heart's mitral valve leaks. The goal is to see if the implant can reduce the leak and improve symptoms. About 15 participants will receive the …
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Polares Medical SA • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New heart scan may sharpen surgery predictions
Knowledge-focused Not yet recruitingThis study looks at whether a special ultrasound technique (speckle tracking) can better predict survival and heart problems after mitral valve surgery compared to the current standard method. Researchers will follow 300 adults with severe mitral regurgitation who are having surg…
Matched conditions: MITRAL REGURGITATION
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 17, 2026 02:15 UTC
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Could a tiny hole in the heart fix post-surgery symptoms?
Knowledge-focused Not yet recruitingThis study looks at whether making a small opening between the upper heart chambers during mitral valve surgery can prevent heart failure symptoms after the operation. It will enroll 50 adults with severe mitral regurgitation who are already scheduled for surgery. Half will get t…
Matched conditions: MITRAL REGURGITATION
Phase: NA • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Tiny heart monitor to uncover silent rhythm problems in valve disease patients
Knowledge-focused Not yet recruitingThis study will use a small device implanted under the skin to continuously monitor the heart rhythm of 100 people with moderate-to-severe mitral valve regurgitation (a leaky heart valve) who have few or no symptoms. The goal is to find out how often hidden atrial fibrillation (a…
Matched conditions: MITRAL REGURGITATION
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC