Heart valve trial: fix both leaks at once or just one?
NCT ID NCT07349888
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will enroll 404 people with severe leakage in both the mitral and tricuspid heart valves. Participants will be randomly assigned to have either both valves repaired at once using a catheter-based device, or only the mitral valve repaired. The goal is to see which approach leads to better survival, fewer heart-related hospital stays, and improved quality of life over one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter Edge-to-Edge Repair (TEER) device
What this could lead to
If it works, this could show that repairing both leaky heart valves at once is better than fixing only one, leading to fewer hospital visits and better quality of life for patients.
What could go wrong
This trial hasn't started yet, and it's not a cure—patients will still need lifelong medication. The procedure itself carries risks like bleeding or valve damage, and the benefit over standard care is unproven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.