Microbubbles may replace needles for heart pressure checks

NCT ID NCT07416279

Recruiting now Diagnosis Sponsor: King's College London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether ultrasound contrast agents (microbubbles) can estimate pressure inside the heart, potentially replacing invasive catheters. Ten adults with suspected heart disease will receive a standard ultrasound with contrast while also having a catheter for comparison. The goal is to see if the microbubble signal matches catheter readings and can be calibrated to measure pressure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SonoVue (ultrasound contrast agent)
What this could lead to: If successful, this could lead to a non-invasive way to measure heart pressure using ultrasound, reducing the need for catheter procedures.
What could go wrong: This is a very early, small study with only 10 participants. The technique may not be accurate enough to replace catheters, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC CATHETERISATION HEART DISEASE HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION

Microbubbles may replace needles for heart pressure checks

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

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