Exercise as medicine: can a tailored workout program reduce hospital visits for heart failure patients?
NCT ID NCT07727096
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether a year-long, supervised exercise program — including aerobic, resistance, and breathing exercises — can improve outcomes for people with heart failure with preserved ejection fraction (HFpEF). Participants are randomly assigned to either usual care or usual care plus the exercise program. The study tracks hospitalizations, quality of life, and physical function over 12 months to see if exercise makes a meaningful difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a structured, multimodal exercise-based cardiac rehabilitation program including aerobic exercise, resistance training, inspiratory muscle training, and lifestyle counselling
- What this could lead to
- If it works, this could establish exercise-based cardiac rehabilitation as a standard part of care for patients with HFpEF, potentially reducing hospitalizations and improving daily life.
- What could go wrong
- This is a behavioral intervention, so adherence may vary. The trial is large but still needs to show clear benefits over usual care, which is not guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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INCLIVA
Valencia, 46010, Spain
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