Heart rehab may tweak cell death pathways — a study investigates

NCT ID NCT07722637

Recruiting now Knowledge-focused Sponsor: TC Erciyes University Source: ClinicalTrials.gov ↗

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study examines whether a structured cardiac rehabilitation program — including exercise, education, and lifestyle changes — can influence ferroptosis, a form of regulated cell death, in people with coronary artery disease. Researchers will compare gene expression and blood markers related to ferroptosis among three groups: patients who undergo rehab, those who decline it, and healthy volunteers. The goal is to uncover whether rehab's benefits extend to the molecular level, potentially opening new avenues for heart disease management.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a supervised cardiac rehabilitation program including exercise, education, and lifestyle changes
What this could lead to: If successful, this could reveal a new biological pathway through which cardiac rehabilitation benefits the heart, potentially leading to more targeted therapies.
What could go wrong: This is an early-stage observational study with a small sample size. It measures biomarkers, not clinical outcomes, so any link to real-world benefits remains uncertain.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC REHAB CORONARY ARTERY DISEASE (CAD) FERROPTOSIS

Contacts and locations

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Locations

Erciyes University Faculty of Medicine
RECRUITING

Kayseri, Kayseri, 38039, Turkey (Türkiye)

Contact Phone: •••-•••-•••• Email: •••••@•••••

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