CORONARY ARTERY DISEASE (CAD)

This study compares two treatments for completely blocked heart arteries: drug-coated balloons versus traditional stents. Researchers want to see if balloons (which leave no metal behind) work as well as stents at keeping arteries open long-term. The trial involves 200 patients w…

This study aims to find the best way to fix a heart stent that has re-narrowed because it didn't fully expand during the original procedure. Researchers will compare a newer method using sound waves (intravascular lithotripsy) against the standard method of using high-pressure ba…

This study is monitoring 3000 patients who receive the Coroflex ISAR NEO heart stent to confirm its long-term safety and effectiveness in real-world use. It follows patients for up to 2 years after their procedure to track complications and how well the stent works. The goal is t…

This study is monitoring the safety and performance of the SUPRAFLEX CRUZ heart stent in real-world patients with multi-vessel coronary artery disease. It will follow over 500 patients who receive the stent as part of their standard care. The main goal is to confirm the device wo…

This study looks at the safety of using the ulnar artery in the wrist for heart procedures when the usual radial artery is blocked from past surgeries. Researchers will follow 127 adults to see if this alternative access point causes serious complications or changes in hand stren…

This large study is testing whether adding a low-dose anti-inflammatory drug called colchicine to standard heart medications can better prevent serious heart problems. It will involve about 3,800 adults with stable coronary artery disease who have plaque buildup in their arteries…

This study is comparing two methods to keep blood pressure stable during a specific type of heart bypass surgery that is done without stopping the heart. One method uses a simple technique of raising the patient's legs, while the other uses only a standard medication. The goal is…

This study is testing a new imaging injection called XTR004 to see if it can better detect significant blockages in the heart's arteries. It will involve about 395 adults with suspected or known stable coronary artery disease. The main goal is to compare the accuracy of pictures …

This study is testing whether a new artificial intelligence (AI) tool can help find hidden coronary artery disease by analyzing a person's facial photo. It will enroll about 1,400 adults who are at higher risk for heart disease due to diabetes, high blood pressure, or being over …

This study aims to understand how people with coronary artery disease (CAD) perform during arm exercises compared to leg exercises. Researchers will measure fitness levels, muscle oxygen use, breathing effort, and feelings of fatigue in 30 participants during different exercise t…

This study is collecting information to see how a new planning tool called PCI Navigator affects how doctors prepare for and perform heart artery stenting procedures. It will enroll 5,000 patients with coronary artery disease who are scheduled for elective stenting. The registry …

This study aims to understand when chest pain starts during different heart artery blockages. Researchers will work with 60 people who have stable chest pain and two narrowed heart arteries. During a heart catheter procedure, they'll temporarily block each artery while participan…

This study aims to understand how a common heart procedure (stent placement) affects erectile function in men. It will compare 100 men who had the procedure after a heart attack to those who had it for stable chest pain. Researchers will track changes in sexual function, depressi…

This study is testing whether a new type of ultrasound measurement taken inside the heart's arteries can help predict which patients with coronary artery disease might have serious heart problems within a year. Researchers will enroll 494 patients who have blockages in all three …

This study aims to understand how heart disease develops over time in people with type 2 diabetes. Researchers will follow 1,000 participants who have already had a detailed heart scan, repeating the scan to measure changes in plaque buildup in their arteries. By tracking these c…

This study aims to see if data from a Fitbit, like heart rate and steps, can help assess and predict a person's risk for heart disease. For six months, 100 adults will wear a Fitbit and have their heart health checked three times. The goal is to learn if wearable devices can be u…