Balloons may beat stents for tough heart blockages

NCT ID NCT07463664

Recruiting now Disease control Sponsor: The First Affiliated Hospital of Zhengzhou University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two treatments for people with completely blocked heart arteries (chronic total occlusions). One group gets a drug-coated balloon, with or without a stent; the other gets standard stents. The goal is to see if the balloon approach keeps arteries open just as well, while possibly reducing the number of stents needed. About 200 participants will be followed for at least 9 months with repeat imaging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: drug-coated balloon (DCB) and drug-eluting stent (DES)
What this could lead to: If successful, this could offer a stent-free or stent-reduced option for treating chronic total blockages in heart arteries, potentially lowering long-term complications.
What could go wrong: This is a mid-stage trial with 200 participants, so results may not apply to all patients. The procedure carries standard risks like vessel injury or re-blockage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

arterial occlusion coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC TOTAL OCCLUSION (CTO) CHRONIC TOTAL OCCLUSIONS OF CORONARY ARTERIES CORONARY ARTERY DISEASE (CAD)

Contacts and locations

Locations

Anyang District Hospital
RECRUITING

Anyang, Henan, 455000, China
Fuwai Hospital Chinese Academy of Medical Sciences (CAMS)
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100037, China
Huaihe Hospital of Henan University
RECRUITING

Kaifeng, Henan, 475000, China
Jincheng People's Hospital
RECRUITING

Jincheng, Shanxi, 048026, China
Kaifeng Central Hospital
RECRUITING

Kaifeng, Henan, 475000, China
Nanyang City Center Hospital
NOT_YET_RECRUITING

Nanyang, Henan, 473000, China
People's Hospital of Zhengzhou
NOT_YET_RECRUITING

Zhengzhou, Henan, 450053, China
Puyang People's Hospital
RECRUITING

Puyang, Henan, 457099, China
The First Affiliated Hospital of Henan University of CM
NOT_YET_RECRUITING

Zhengzhou, Henan, 450000, China
The First Affiliated Hospital of Henan University of Science and Technology
RECRUITING

Luoyang, Henan, 471003, China
The People's Hospital of Jiaozuo
NOT_YET_RECRUITING

Jiaozuo, Henan, 454002, China
The Second People's Hospital of Pingdingshan
RECRUITING

Pingdingshan, Henan, 467000, China
The second people's Hospital of Jiyuan
RECRUITING

Jiyuan, Henan, 454000, China
Tianjin Fourth Central Hospital
NOT_YET_RECRUITING

Tianjin, Tianjin Municipality, 300074, China
Xinyang Central Hospital
NOT_YET_RECRUITING

Xinyang, Henan, 464000, China
Yellow River Sanmenxia hospital
NOT_YET_RECRUITING

Sanmenxia, Henan, 472000, China
Zhengzhou Central Hospital
NOT_YET_RECRUITING

Zhengzhou, Henan, 450000, China
Zhoukou Central Hospital
RECRUITING

Zhoukou, Henan, 466000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.