Balloons may beat stents for tough heart blockages
NCT ID NCT07463664
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for people with completely blocked heart arteries (chronic total occlusions). One group gets a drug-coated balloon, with or without a stent; the other gets standard stents. The goal is to see if the balloon approach keeps arteries open just as well, while possibly reducing the number of stents needed. About 200 participants will be followed for at least 9 months with repeat imaging.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
drug-coated balloon (DCB) and drug-eluting stent (DES)
What this could lead to
If successful, this could offer a stent-free or stent-reduced option for treating chronic total blockages in heart arteries, potentially lowering long-term complications.
What could go wrong
This is a mid-stage trial with 200 participants, so results may not apply to all patients. The procedure carries standard risks like vessel injury or re-blockage.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Anyang District Hospital
RECRUITINGAnyang, Henan, 455000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fuwai Hospital Chinese Academy of Medical Sciences (CAMS)
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100037, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Huaihe Hospital of Henan University
RECRUITINGKaifeng, Henan, 475000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Jincheng People's Hospital
RECRUITINGJincheng, Shanxi, 048026, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Kaifeng Central Hospital
RECRUITINGKaifeng, Henan, 475000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nanyang City Center Hospital
NOT_YET_RECRUITINGNanyang, Henan, 473000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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People's Hospital of Zhengzhou
NOT_YET_RECRUITINGZhengzhou, Henan, 450053, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Puyang People's Hospital
RECRUITINGPuyang, Henan, 457099, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Henan University of CM
NOT_YET_RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The First Affiliated Hospital of Henan University of Science and Technology
RECRUITINGLuoyang, Henan, 471003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The People's Hospital of Jiaozuo
NOT_YET_RECRUITINGJiaozuo, Henan, 454002, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The Second People's Hospital of Pingdingshan
RECRUITINGPingdingshan, Henan, 467000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The second people's Hospital of Jiyuan
RECRUITINGJiyuan, Henan, 454000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Fourth Central Hospital
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 300074, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Xinyang Central Hospital
NOT_YET_RECRUITINGXinyang, Henan, 464000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yellow River Sanmenxia hospital
NOT_YET_RECRUITINGSanmenxia, Henan, 472000, China
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Zhengzhou Central Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhoukou Central Hospital
RECRUITINGZhoukou, Henan, 466000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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