New heart scan could spot hidden blockages without surgery

NCT ID NCT07439133

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether an injection called XTR004, used with a PET scan, can accurately detect blood flow-blocking narrowings in heart arteries. About 395 adults with known or suspected stable coronary artery disease will receive the injection and undergo imaging. The results will be compared to standard angiography to see if this less invasive method is reliable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

XTR004 (99mTechnetium Sestamibi)

What this could lead to

If successful, this could provide a more accurate, non-invasive way to detect dangerous artery blockages, potentially reducing the need for invasive procedures.

What could go wrong

This is a diagnostic trial, not a treatment. Even if accurate, it may not change patient outcomes. The test involves radiation exposure, and results depend on interpretation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital, Capital Medical University

    RECRUITING

    Beijing, China

  • Beijing Tongren Hospital

    RECRUITING

    Beijing, China

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, China

  • TEDA International Cardiovascular Hospital

    RECRUITING

    Tianjin, China

  • The First People's Hospital of Foshan

    RECRUITING

    Foshan, China