HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Clinical trials for HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION explained in plain language.
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Could a diabetes pill ease pressure on failing fontan hearts?
Disease control Recruiting nowThis study tests whether dapagliflozin, a drug used for diabetes and heart failure, can lower vein pressure in adults with a failing Fontan circulation. About 27 participants will take the drug or a placebo for 3 months. The goal is to see if it helps the heart pump blood more ea…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Heart fix combo: ablation plus exercise may boost oxygen in stiff heart failure
Disease control Recruiting nowThis study looks at whether combining a heart procedure called ablation with a 12-week home exercise program can improve how well the body uses oxygen in people with a type of heart failure (HFpEF) and a common heart rhythm problem (atrial fibrillation). About 40 participants wil…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: Technical University of Munich • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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AI-Powered patch could replace ultrasound for heart checkups
Diagnosis Recruiting nowThis study tests an artificial intelligence program that analyzes heart rhythm data from a small, wearable patch to estimate how well the heart pumps blood. Researchers will compare the AI's results to standard ultrasound in 2,000 adults. If accurate, this could offer a simpler, …
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: Peerbridge Health, Inc • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Microbubbles may replace needles for heart pressure checks
Diagnosis Recruiting nowThis study tests whether ultrasound contrast agents (microbubbles) can estimate pressure inside the heart, potentially replacing invasive catheters. Ten adults with suspected heart disease will receive a standard ultrasound with contrast while also having a catheter for compariso…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: King's College London • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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Heart failure study tests if a coach — in person or on video — boosts exercise and Well-Being
Symptom relief Recruiting nowThis study looks at whether meeting with a coach, either in person or by video, helps adults with a certain type of heart failure (HFpEF) exercise more regularly. About 300 participants will be split into three groups for 18 months: one with no coach, one with in-person coaching,…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can remote exercise and weight loss boost heart failure Patients' stamina?
Symptom relief Recruiting nowThis study tests whether a tailored, home-based exercise program (with or without weight loss medications) can improve exercise capacity and quality of life in 120 adults with heart failure with preserved ejection fraction (HFpEF). Participants will follow exercise videos and mee…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Game on: social rewards may get heart patients moving
Symptom relief Recruiting nowThis study tests whether adding game-like elements and social rewards (like support or friendly competition) can motivate people with a type of heart failure (HFpEF) to walk more. About 270 adults will use a step tracker and be randomly assigned to one of two gamification program…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New device aims to measure hidden heart stiffness
Knowledge-focused Recruiting nowThis observational study tests a new device (eMyosound LYRA) that uses sound waves to measure stiffness in the heart and liver. Researchers will compare 150 people—some with heart failure, some with a rare heart condition called ATTR-CM, and some healthy volunteers. The goal is t…
Matched conditions: HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION
Sponsor: eMyosound SAS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC