Can remote exercise and weight loss boost heart failure Patients' stamina?

NCT ID NCT07223242

Recruiting now Symptom relief Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a tailored, home-based exercise program (with or without weight loss medications) can improve exercise capacity and quality of life in 120 adults with heart failure with preserved ejection fraction (HFpEF). Participants will follow exercise videos and meet weekly with a coach. The goal is to find a practical, accessible way to help people with HFpEF feel better and be more active.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: exercise training (moderate-intensity continuous training and resistance training) and weight loss medications (semaglutide or tirzepatide)
What this could lead to: If successful, this could offer a practical, home-based exercise program to help people with HFpEF feel better, move more easily, and improve their daily life.
What could go wrong: This is a mid-stage trial with only 120 participants, so results may not apply to everyone. The exercise program is remote, so adherence and effectiveness may vary.

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Conditions

The condition(s) this trial relates to.

Diabetic Cardiomyopathies diastolic heart failure Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC CARDIOMYOPATHIES HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION

Contacts and locations

Locations

University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75209, United States

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