Could a diabetes pill ease pressure on failing fontan hearts?

NCT ID NCT06762964

Recruiting now Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether dapagliflozin, a drug used for diabetes and heart failure, can lower vein pressure in adults with a failing Fontan circulation. About 27 participants will take the drug or a placebo for 3 months. The goal is to see if it helps the heart pump blood more easily.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure univentricular cardiopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FONTAN CIRCULATION HFPEF - HEART FAILURE WITH PRESERVED EJECTION FRACTION SINGLE VENTRICLE HEART DISEASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

Contact

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