SINGLE VENTRICLE HEART DISEASE
Clinical trials for SINGLE VENTRICLE HEART DISEASE explained in plain language.
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Could a diabetes pill ease pressure on failing fontan hearts?
Disease control Recruiting nowThis study tests whether dapagliflozin, a drug used for diabetes and heart failure, can lower vein pressure in adults with a failing Fontan circulation. About 27 participants will take the drug or a placebo for 3 months. The goal is to see if it helps the heart pump blood more ea…
Matched conditions: SINGLE VENTRICLE HEART DISEASE
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could a heart pill help fontan teens breathe easier during exercise?
Disease control Recruiting nowThis study tests whether the drug udenafil can improve exercise ability in adolescents aged 12-18 who have had the Fontan procedure for single ventricle heart disease. Participants will take udenafil or a placebo daily for 26 weeks, and their exercise capacity will be measured. T…
Matched conditions: SINGLE VENTRICLE HEART DISEASE
Phase: PHASE3 • Sponsor: Mezzion Pharma Co. Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Researchers study digoxin dosing in infants with rare heart condition
Knowledge-focused Recruiting nowThis study looks at how the heart medication digoxin is processed in infants born with single ventricle heart disease. Researchers will collect blood samples during routine care to measure drug levels. The goal is to better understand dosing, but the study does not change the inf…
Matched conditions: SINGLE VENTRICLE HEART DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC