FONTAN CIRCULATION
Clinical trials for FONTAN CIRCULATION explained in plain language.
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Could a diabetes pill ease pressure on failing fontan hearts?
Disease control Recruiting nowThis study tests whether dapagliflozin, a drug used for diabetes and heart failure, can lower vein pressure in adults with a failing Fontan circulation. About 27 participants will take the drug or a placebo for 3 months. The goal is to see if it helps the heart pump blood more ea…
Matched conditions: FONTAN CIRCULATION
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Heart drug dosing study aims to protect fontan Patients' livers
Knowledge-focused Recruiting nowThis study looks at how liver congestion and scarring affect the way the body processes two common drugs, sildenafil and pravastatin, in people with Fontan circulation. Researchers will give a single dose of each drug to 15 participants aged 8 and older and measure drug levels in…
Matched conditions: FONTAN CIRCULATION
Phase: PHASE1 • Sponsor: Children's Mercy Hospital Kansas City • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC