HEART DISEASE

This study tests a drug called orticumab in 240 people who had a heart attack and still have high inflammation in their heart arteries. The goal is to see if orticumab can lower that inflammation better than a placebo over 6 months, using special CT scans to measure changes. Part…

This study looks at whether giving people healthy prepared meals and education helps them eat better compared to just getting physical activity coaching. About 120 adults in Anson County who have or are at risk for chronic diseases like obesity, diabetes, or heart disease will ta…

This study tests a new device called the Supira System in 45 people with heart failure and low heart function who need a high-risk heart procedure. The device is designed to help pump blood during and after the procedure, potentially reducing complications. The goal is to see if …

This study looks at whether training doctors to quickly start and adjust four types of heart failure medications while patients are still in the hospital leads to better long-term treatment. About 438 adults with heart failure and reduced pumping function will be followed after d…

This study tests whether artificial intelligence (AI) can quickly and accurately spot heart disease using simple, portable devices. Researchers will screen about 19,300 people, including teens, adults, and pregnant women, using AI-enhanced EKGs and ultrasound. The goal is to see …

This study checks if a small chest-patch that uses light to measure blood pressure works as well as the standard arm-cuff method over 24 hours. About 600 adults with or without high blood pressure will wear both devices. The goal is to see if the patch is accurate, easy to use, a…

This study aims to help Latino families living near the U.S.-Mexico border become more physically active and fit. About 290 parents and children ages 6 to 11 will take part in a community-based program at local centers. The goal is to reduce high rates of obesity and heart diseas…

This study collects genetic and health information from 3,000 people to help doctors choose safer and more effective medications. Participants have conditions like diabetes, high blood pressure, heart disease, or cancer, and take multiple medications. The goal is to learn how gen…

This study follows 750 people with sickle cell disease who have received curative therapies (like stem cell transplants) to see how their heart, lung, and kidney health changes over time compared to those on standard treatment. The goal is to understand if these therapies improve…

This study looks at whether men and women maintain physical activity differently during and after cardiac rehabilitation. Researchers will track daily steps and fitness levels of 150 participants over 10 months. The goal is to understand barriers to staying active, which can help…

This early study tests if ultrasound contrast agents (microbubbles) can estimate pressure inside the heart, potentially replacing the need for a catheter. Ten adults with suspected heart disease will receive a standard contrast injection and an ultrasound scan. Researchers will c…

This study is testing whether a smartphone app can accurately predict heart structure and function from a photo of an electrocardiogram (ECG). Researchers will compare the app's predictions to standard echocardiograms (heart ultrasounds) in 478 adults. If successful, this could a…

This study is testing a tool called Transit-Time Flow Measurement (TTFM) that uses sound waves during heart bypass surgery to check blood flow through the new grafts. The goal is to see if using this tool helps prevent grafts from failing. About 1,242 adults having their first no…

This study looks at how a person's genes and their environment (like pollution, diet, and lifestyle) work together to cause common diseases such as diabetes, heart disease, and asthma. Researchers are collecting health questionnaires and genetic data from 25,000 adults to build a…