Mind-Controlled exoskeleton reads muscle signals to restore natural walking after stroke

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Healthy Participants: * Age from 18 to 80 years * No history of a brain and/or skull lesion * Normal hearing and vision, both can be corrected * Able to understand and give informed consent * No neurological disorders * Absence of pathology that could cause abnormal movements of extremities (e.g., * epilepsy, stroke, marked arthritis, chronic pain, musculoskeletal injuries) * Able to understand and speak English * Height between 3 foot 6 inches (1.1 meters) and 6 foot 9 inches (2.1 meters) Inclusion Criteria for Participants Post-stroke: * Age from 18 to 80 years * History of unilateral, supratentorial, ischemic or hemorrhage stroke greater than 6 months * Ability to walk independently on level ground, allowed to use assistive device or bracing * as needed * Medically stable * No planned surgeries, medical treatments or outpatient therapy during the study period * Normal hearing and vision, both can be corrected * Able to understand and give informed consent * Able to understand and speak English * Height between 3 foot 6 inches (1.1 meters) and 6 foot 9 inches (2.1 meters) Exclusion Criteria for Healthy Participants: * Weight over 220 lbs * Pregnancy (ruled out by pregnancy questionnaire) * Any neurological diagnoses or medications influencing brain function * History of significant head trauma (i.e., extended loss of consciousness, neurological * sequelae) * Known structural brain lesion * Significant other disease (heart disease, malignant tumors, mental disorders) * Non prescribed drug use (as reported by subject) * History of current substance abuse (exception: current nicotine use is allowed) * Recreational marijuana * Dementia; severe depression; or prior neurosurgical procedures * Failure to perform the behavioral or locomotor tasks * Prisoners Exclusion Criteria for Participants Post-Stroke: * Weight over 220 lbs * Pregnancy (ruled out by pregnancy questionnaire) * Botox (botulinum toxin) injection to lower limbs within the prior 3 months, or planned * injection during study period. * History of current substance abuse (exception: current nicotine use is allowed) * Reduced cognitive function * Severe aphasia * Prisoners * Co-existence of other neurological diseases (ex: (Parkinson's disease, traumatic brain * injury, multiple sclerosis, etc.) * Mixed or complex tremors * Severe hip, or knee arthritis * Osteoporosis (as reported by subject) * Medical (cardiac, renal, hepatic, oncological) or psychiatric disease that would * interfere with study procedures for HD-EMG