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Can targeted electrical stimulation or task practice better restore leg movement after a stroke?

NCT ID NCT07718776

Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests two rehabilitation techniques — synergy-based electrical stimulation and task-oriented training — to see which better improves leg movement and mobility in people who had a stroke 1 to 6 months ago. Participants, aged 40 to 60, will receive one of the two approaches alongside standard therapy for six weeks. Researchers will measure changes in motor recovery, walking speed, and balance to compare the effectiveness of each method.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
synergy-based electrical stimulation or task-oriented training
What this could lead to
If one approach proves more effective, it could point toward a better rehabilitation strategy for regaining leg function after a stroke.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply to all stroke survivors. Both interventions are generally low-risk, but electrical stimulation may cause discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 40 to 60 years * Both Male and Female participants * In the sub-acute phase of stroke (1-6 months post-stroke) with lower limb motor impairment but with the ability to initiate at least trace muscle contraction (Grade ≥ 1). * Participants must have the ability to understand and follow simple verbal commands with the Mini-Mental State Examination (MMSE) ≥ 26. * Participants must have a first-ever ischemic and hemorrhagic stroke in the sub-acute stage. * Participants who are functionally ambulatory and able to walk a minimum of 10 feet, with or without the use of assistive devices with a Functional Ambulation Category (FAC) score ≥ 2. Exclusion Criteria: * Participants have severe cognitive impairment and an inability to understand or follow instructions, and severe sensory impairment with profound sensory loss in the lower limb affecting balance or feedback-based training. * Participants having orthopedic limitations like recent fractures, joint deformities, or surgeries affecting the lower limbs. * Participants having implanted electrical devices like pacemakers are contraindicated for electrical stimulation * Participants having a history of more than one stroke episode and or multiple infarcts.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lower limb Post-stroke

Contacts and locations

Locations

  • Study site

    Lahore, Punjab Province, 54000, Pakistan

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