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Massive 10,000-person study to reveal how sleep apnea treatment affects heart health

NCT ID NCT05115994

Ongoing Knowledge-focused Sponsor: Vastra Gotaland Region Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 10,000 people with both obstructive sleep apnea and high blood pressure over many years. Researchers will track how well patients use CPAP machines and blood pressure medications, and whether this reduces the chance of heart attacks, strokes, heart failure, or death. The goal is to find the best treatment strategies to protect the heart in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Continuous positive airway pressure (CPAP) device and antihypertensive medications
What this could lead to
If successful, this could clarify which treatments best prevent heart attacks, strokes, and death in people with both sleep apnea and high blood pressure.
What could go wrong
This is an observational registry study, not a controlled trial, so it can show links but not prove cause and effect. Results may take years and might not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiac arrest Death heart failure hypertensive disorder obstructive sleep apnea syndrome Patient Compliance stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEATH, CARDIAC HEART FAILURE HYPERTENSION OBSTRUCTIVE SLEEP APNEA STROKE TREATMENT COMPLIANCE

Contacts and locations

Locations

  • Sahlgrenska University Hospital

    Gothenburg, Västra Götaland County, 413 45, Sweden

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