Vastra Gotaland Region

This study tests whether a special balloon coated with the drug paclitaxel (Optilume) can prevent urethral strictures from returning better than a standard balloon. About 230 adults with a recurrent stricture after prior treatment will be randomly assigned to one of the two ballo…

This study tests a comprehensive health program for 644 people with psychotic disorders. The program provides regular check-ups, motivational tools, and support from a team of health professionals to improve heart health and quality of life. Researchers will compare the program t…

This study compares having one laser treatment session versus several sessions for people with proliferative diabetic retinopathy, a serious eye condition that can lead to blindness. Researchers want to see which approach is safer and works better. About 40 adults with diabetes a…

This study tests whether adding another chemotherapy drug (lomustine) to the standard treatment can help people with a specific type of glioblastoma, a fast-growing brain cancer, live longer. About 200 adults aged 18-70 with newly diagnosed, MGMT-methylated glioblastoma will be r…

This study tests whether one dose of the immunotherapy drug pembrolizumab, given before standard surgery, can shrink or eliminate tumors in people with stage IIb/c melanoma. About 30 adults with thick melanomas that haven't spread to lymph nodes will receive either pembrolizumab …

This study compares two treatments for arm muscle tightness (spasticity) caused by stroke, spinal cord injury, or brain injury. Thirty adults will receive both surgery and botulinum toxin injections at different times, so each person acts as their own comparison. The goal is to s…

This study tests whether adding high-dose radiation to standard drug therapy can help people with non-small cell lung cancer that has spread to up to 5 spots. About 240 participants will be randomly assigned to receive either standard treatment alone or standard treatment plus ra…

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older. Researchers will compare the program to usual care in 132 participants, tracking suicide attempts and deaths over two years. The goal is to see if this brief intervention …

This study tests a program called WOMENinMOTION that teaches pregnant women how to manage pelvic girdle pain and stay physically active. The goal is to prevent the pain from becoming chronic after childbirth. About 592 pregnant women will either receive the program plus usual car…

This study tests whether a person-centred care (PCC) program, delivered by phone and online, can reduce mental fatigue and sick leave in adults with Graves' disease. About 220 people who have had their first episode of Graves' will either receive usual care or usual care plus the…

This study tests whether a personalized physical activity plan, guided by a physiotherapist, can improve quality of life and overall health in people who had surgery for a non-functioning pituitary adenoma. About 120 participants will be randomly assigned to either receive the ex…

This study tests whether a special course on managing mental fatigue can improve brain fog, exhaustion, and quality of life in people with Graves' disease. About 96 adults with persistent mental fatigue will either take the course plus standard care or receive standard care alone…

This study follows 380 women for a year after vaginal childbirth to see how pelvic floor muscles and tissues recover. It also tests whether early, personalized pelvic floor muscle training can improve symptoms like urine leakage and pelvic organ prolapse compared to standard care…

This study looks at whether having a nurse or pharmacist do the first check for a sore throat can cut down on unnecessary antibiotic prescriptions. About 450 people with sore throats will be checked by a doctor, nurse, or pharmacist to see if guidelines are followed better. The g…

This study follows 400 people who have urologic cancer surgery with lymph node removal to see how often leg swelling (lymphedema) happens. Researchers use questionnaires and special devices to measure swelling and tissue fluid over two years. The goal is to better understand this…

This study aims to understand why some people with Graves' disease continue to experience mental fatigue even after their thyroid levels return to normal. Researchers will compare blood and spinal fluid samples from 180 participants—60 with mental fatigue, 60 without, and 60 heal…

This study interviews parents of 12–15 children aged 6–12 with functional constipation to learn how physical activity impacts their child's condition. Researchers want to understand if exercise can help relieve symptoms, since current treatments focus on medication and diet. The …

This study looks at 300 women aged 50 and older who have blood in their urine along with a bladder infection. Researchers want to see if these women need the full set of cancer tests (like a camera in the bladder and CT scans) or if they can safely skip them. The goal is to find …

This study tests a new camera-based system that can measure pulse, blood pressure, breathing rate, oxygen levels, and body temperature without touching the patient. The goal is to see if this contactless method works as well as traditional devices, which require physical contact …

This study looks at people who had surgery for a torn peroneal tendon in their ankle. Participants will be split into two groups, each following a different recovery plan after surgery. Researchers will measure pain, movement, and strength over two years to see which plan helps p…

This study is looking for 340 people with suspected giant cell arteritis (GCA), a condition that causes inflammation in blood vessels and is usually treated with long-term steroids. The goal is to find better ways to predict who will have relapses and to monitor the disease using…

This study involves 150 people with diabetic macular edema (DME) who are either starting treatment with anti-VEGF injections or a dexamethasone implant, or have not been treated before. Researchers will measure various substances in the blood and use eye scans to see if these mar…

This study tests a magnetic tracer and clip to help surgeons locate lymph nodes in breast cancer patients before chemotherapy. About 459 adults will receive the injection before surgery to see how well it works. The goal is to improve detection and reduce the need for more invasi…