Vastra Gotaland Region

This study tests whether giving dry plasma to people with life-threatening bleeding before they reach the hospital can improve survival. Researchers will compare dry plasma to standard fluids in 650 adults with signs of bleeding shock. The goal is to see if this approach reduces …

This study tests a modified version of the Crohn's Disease Exclusion Diet (CDED) in 30 children aged 6-18 with mild-to-severe Crohn's disease. The goal is to see if the Nordic CDED can help children achieve remission without steroids, while also improving diet adherence and quali…

This early-stage trial tests whether giving patients their own lab-grown immune cells (tumor-infiltrating lymphocytes) can safely treat metastatic melanoma that has spread. The study will enroll 18 adults with either uveal or cutaneous melanoma. The main goal is to check for side…

This study tests a 26-week video coaching program to help adult survivors of childhood cancer eat better and exercise more. The goal is to improve quality of life and reduce long-term health risks like heart disease. About 900 participants will be randomly assigned to receive the…

This study looks at 144 children aged 9-13 with a large overbite (overjet ≥6 mm) to see if early treatment with special appliances like headgear-activator, twin block, or Invisalign MA is better than waiting and using standard braces later. The goal is to find which approach redu…

This study is for people with early-stage rectal cancer. It tests whether using chemoradiotherapy (a combination of chemotherapy and radiation) can completely eliminate the tumor, allowing patients to safely avoid surgery and keep their rectum. Participants can choose between sta…

This study looks at a rare condition called non-progressive congenital ataxia, which affects movement and coordination in young children. Researchers will use detailed checkups, brain scans, and genetic tests to better understand the condition and improve diagnosis. The goal is t…

This study looks at whether a physiotherapist can accurately diagnose knee pain through a video call instead of an in-person visit. Researchers will compare diagnoses made using a function-based assessment (no special tests) in both settings. The goal is to see if video consultat…

This study tests two digital tools to help primary care doctors better diagnose middle ear infections (otitis media). One is a game-like training program for physicians, and the other is an AI system that analyzes ear images. About 200 patients with ear symptoms will take part ac…

This study tests whether a magnetic tracer (Magtrace) works as well as the standard radioactive dye plus blue dye for finding sentinel lymph nodes in people with melanoma. About 254 adults will get both tracers before surgery, and doctors will compare how often each method finds …

This study tests whether 12 weeks of high-intensity interval training and strength training can improve heart and metabolic health in people with psoriatic arthritis. Researchers will also measure effects on fitness, pain, fatigue, and quality of life. The trial aims to enroll 88…

This study tests a faster version of a brain stimulation treatment called iTBS for people with depression. Instead of daily sessions for weeks, participants receive 30 short sessions over 5 to 14 days. The goal is to see if this quicker approach works well and is tolerable in rou…

This study looks at whether providing acute medical care at home for people aged 75 and older is as good as going to the emergency department. Researchers will compare healthcare use and death rates between the two groups. The goal is to see if home-based care can be a safe and e…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study checks if a short, easy bike exercise test gives consistent results in 40 people with hip or knee osteoarthritis. Participants will take the test twice, one to two weeks apart. If reliable, this test could become a standard tool for assessing fitness in osteoarthritis …

This study will check how often the blood pressure monitors in the ICU are not positioned correctly, which can lead to wrong readings. Researchers will watch 60 critically ill adults on breathing machines and blood pressure support for 8 hours. They will see if these small errors…

This study looks at how common joint hypermobility (being extra flexible) and pain are in 100 female patients aged 13–25 with anorexia nervosa or atypical anorexia. Researchers want to know if hypermobility causes pain and if jaw joint problems make eating harder. Participants wi…

This study watches 300 premature babies born before 37 weeks who need surfactant—a natural substance that helps their lungs stay open. Doctors will compare four different ways to give the medicine (via breathing tube, thin catheter, or mask) to see which leads to less need for a …

This study aims to understand how adults with Fabry disease who are not yet receiving treatment experience their quality of life. Researchers will interview 35 participants in Sweden to learn about symptoms, daily challenges, and healthcare experiences. The goal is to identify ne…

This study explores whether a health app and online chats with a dental hygienist can motivate teenagers (ages 16-17) to improve their oral hygiene and reduce gingivitis (gum inflammation). About 25 teens with signs of gum disease will use the app and share their experiences. The…