Ventilator pressure showdown: which setting saves lungs best?
NCT ID NCT07188038
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how different levels of positive end-expiratory pressure (PEEP) on a ventilator affect the diaphragm and lungs in ICU patients with respiratory failure. Twenty-five adults on pressure support ventilation will each receive low, medium, and high PEEP for short periods. Researchers will measure diaphragm activity, breathing effort, and lung mechanics using special catheters and ultrasound.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors choose the best ventilator settings to protect the lungs and diaphragm in critically ill patients.
What could go wrong
This is a small, early-stage study with only 25 participants, so results may not apply to all patients. It measures short-term effects, not long-term outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Central intensivvårdsavdelning, Sahlgrenska University Hospital
Gothenburg, Västra Götaland County, 413 45, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Thorax intensivvårdsavdelning, Område 6, Sahlgrenska University Hospital, Västra Götalandsregionen
Gothenburg, Västra Götaland County, 413 45, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••