RESPIRATORY INSUFFICIENCY

This study is testing a new method to help patients with severe lung failure who are on breathing machines. Researchers want to see if carefully adjusting a muscle-relaxing medication can help these patients breathe more safely on their own. The trial will check if this approach …

This study tests two breathing exercises together in people with ALS to see if they can improve cough strength and lung function. About 34 participants will practice lung volume recruitment and expiratory muscle strength training. The goal is to ease breathing problems, reduce co…

This study is testing a simple device with motion sensors placed on a child's chest and belly to measure how well their breathing is coordinated. The goal is to see if it can detect breathing distress early, even when it's hard to see with the naked eye. About 20 children aged 28…

This study looks at whether combining two simple tests—one that measures breathing patterns and another that checks inflammation and nutrition levels in the blood—can better predict when critically ill patients are ready to be taken off a breathing machine. Researchers will follo…

This study compares three different facemasks used with a breathing machine in 20 people whose lungs are not removing carbon dioxide well. The goal is to see which mask helps the diaphragm work less hard and clears carbon dioxide more effectively. Participants will try each mask …

This large study is testing multiple new treatments for people with severe breathing failure who need oxygen or a ventilator. It will include up to 6,250 participants and use a flexible design to quickly identify which treatments work best. The goal is to improve survival and red…

This study looks at whether patients in the ICU with severe breathing problems can safely eat or drink before they need a breathing tube. Normally, patients are kept fasting to prevent food from getting into the lungs, but this may cause discomfort and malnutrition. The study wil…