RESPIRATORY INSUFFICIENCY

This study tests whether using a high-flow nasal cannula (a device that delivers warm, moist oxygen at high speeds) for 24 hours right after major abdominal surgery can prevent early lung complications like pneumonia or collapsed lungs. About 580 adults having long abdominal surg…

This study tests whether an improved non-invasive ventilation (NIV) mask can lower how often people need to breathe compared to a standard mask. About 60 adults who already use NIV for respiratory problems will try both masks for one hour each. Researchers will measure breathing …

This study looks at whether starting breathing support (non-invasive ventilation) earlier than usual can help people with ALS. About 48 adults recently diagnosed with ALS will either start breathing support early or receive standard care. The goal is to see if early use improves …

This study tests a procedure called cryoablation, which uses cold to temporarily freeze nerves around broken ribs. The goal is to reduce severe pain, improve breathing, and prevent complications like pneumonia. About 30 adults with multiple rib fractures will be randomly assigned…

This study looks at whether the sedative drug dexmedetomidine, given early to older patients (65+) on breathing machines in the ICU, can reduce deaths and confusion compared to a placebo. About 300 participants will receive either the drug or a dummy treatment, and researchers wi…

This study looks at how different levels of pressure from a breathing machine (ventilator) affect the lungs and diaphragm in 25 ICU patients with respiratory failure. Each patient will try three pressure settings to see which one helps them breathe more efficiently and with less …

This study looks at whether using simple breathing measurements during surgery can help doctors decide the best way to close the belly wall after repairing a large hernia. The goal is to reduce serious breathing problems in the first 3 days after surgery. About 50 adults who alre…