ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Clinical trials for ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME) explained in plain language.
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New drug trial aims to help patients with severe lung failure
Disease control Recruiting nowThis Phase 2 trial tests a drug called paridiprubart in hospitalized adults with moderate to severe acute respiratory distress syndrome (ARDS), a serious lung condition. About 200 participants will receive either the drug or a placebo as a single IV dose. The main goal is to see …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2 • Sponsor: PPD Development, LP • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New drug trial aims to boost survival in severe lung failure patients
Disease control Recruiting nowThis study tests a medicine called vilobelimab in adults hospitalized with moderate to severe acute respiratory distress syndrome (ARDS), a life-threatening lung condition. About 200 participants will receive either the drug or a placebo to see if it improves survival and is safe…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2 • Sponsor: PPD Development, LP • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New drug trial aims to improve survival in ARDS patients
Disease control Recruiting nowThis study tests a drug called bevacizumab in hospitalized adults with acute respiratory distress syndrome (ARDS), a severe lung condition. About 200 participants will receive either the drug or a placebo to see if it improves survival and oxygen levels. The goal is to find a saf…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2 • Sponsor: PPD Development, LP • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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New hope for ARDS: major trial tests multiple therapies in hospitalized patients
Disease control Recruiting nowThis study tests several experimental treatments for adults hospitalized with acute respiratory distress syndrome (ARDS), a severe lung condition. About 600 participants will receive either a placebo or an active drug to see if the treatments improve survival and are safe. The go…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE2 • Sponsor: PPD Development, LP • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Can lung imaging guide ventilator settings to save lives in ARDS?
Disease control Recruiting nowThis study tests whether using a lung imaging tool called EIT to set ventilator pressure (PEEP) can improve survival in patients with moderate-to-severe ARDS. The trial will enroll 2400 adults and compare EIT-guided PEEP to the standard method. The main goal is to see if this app…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Southeast University, China • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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New breathing strategy could save lives in ARDS
Disease control Recruiting nowThis study tests whether a personalized ventilation strategy guided by electrical impedance tomography (EIT) can improve survival in adults with acute respiratory distress syndrome (ARDS). About 574 participants will be randomly assigned to receive either EIT-guided ventilation (…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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AI-Powered ventilator coach aims to protect lungs in ICU
Disease control Recruiting nowThis trial tests a real-time algorithm-driven system that gives doctors feedback on ventilator settings to protect the lungs of critically ill patients. The study will include 208 adults on breathing machines with acute respiratory distress syndrome (ARDS). The goal is to see if …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New inhaled drug hopes to heal lungs in ventilator patients
Disease control Recruiting nowThis early-phase trial tests a single inhaled dose of a lab-made protein (Rh-KGF-2) in 24 adults with moderate to severe ARDS who are on ventilators. The goal is to see if the drug is safe and tolerable, and to find the right dose. Participants are split into three dose groups, w…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: EARLY_PHASE1 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New antibody HT31-1 enters human trials for ARDS
Disease control Recruiting nowThis early-stage trial tests a new antibody called HT31-1 in 24 healthy volunteers to see if it is safe and how the body processes it. The antibody targets a protein linked to inflammation in acute respiratory distress syndrome (ARDS), a severe lung condition often caused by infe…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE1 • Sponsor: HTIC, Inc • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Scientists hunt for hidden ARDS subtypes to crack deadly lung failure
Knowledge-focused Recruiting nowThis study will analyze samples from 130 ICU patients with ARDS (a severe lung injury) to better understand why the condition varies so much between people. Researchers will examine lung fluid, blood, and CT scans to identify distinct biological subtypes. The goal is not to test …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: Medical University of Vienna • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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New study aims to personalize ventilator settings for lung injury patients
Knowledge-focused Recruiting nowThis study looks at two different methods for setting the pressure on a breathing machine (ventilator) in people with a serious lung condition called ARDS. The goal is to see which method improves oxygen levels better over 24 hours. About 52 adults with moderate to severe ARDS wi…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Hospital Dr. Franco Ravera Zunino • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Lab study hopes to unlock ARDS treatment using patient blood cells
Knowledge-focused Recruiting nowThis study looks at blood from people with ARDS, a severe lung condition with no specific medicines. Researchers will take immune cells from the blood and test a new blocking agent in the lab to see if it can reduce lung damage. The goal is to learn more about the disease and fin…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Simple chest squeeze may replace High-Tech ventilator settings
Knowledge-focused Recruiting nowThis study tests whether a simple manual chest compression technique works as well as electrical impedance tomography (a special imaging method) to find the best ventilator pressure for people with acute respiratory distress syndrome (ARDS). Thirty adults on ventilators will have…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Centre Hospitalier Saint Joseph Saint Luc de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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ECMO breakthrough? major trial aims to cut deadly complications
Knowledge-focused Recruiting nowThis study is testing different treatments to reduce major complications and improve survival in 600 adults who need ECMO—a machine that does the work of the heart and lungs. Researchers will compare how well these treatments work in the first 28 days. The goal is to find safer, …
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: PHASE3 • Sponsor: Australian and New Zealand Intensive Care Research Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New 3D imaging technique could improve care for ARDS patients
Knowledge-focused Recruiting nowThis study will use a 3D electrical impedance tomography (EIT) device to monitor how lung ventilation and blood flow change when ARDS patients are placed on their stomach (prone position). Researchers will track 30 patients on mechanical ventilation at three time points: lying on…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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New study aims to shorten ventilator time for ECMO patients
Knowledge-focused Recruiting nowThis study looks at whether closely tracking a patient's breathing effort can help doctors decide the best time to remove a life-support machine called ECMO in people with severe lung failure (ARDS). About 50 adults on ECMO will be randomly assigned to have their breathing monito…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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500 ICU patients to be tracked in ARDS Real-World study
Knowledge-focused Recruiting nowThis study will observe 500 people with Acute Respiratory Distress Syndrome (ARDS) in intensive care to understand what factors influence their recovery and survival. Researchers will track deaths, imaging, lab tests, and ventilator use. The goal is to find patterns that could im…
Matched conditions: ARDS (ACUTE RESPIRATORY DISTRESS SYNDROME)
Sponsor: Ming Zhong • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:10 UTC