New inhaled drug hopes to heal lungs in ventilator patients

NCT ID NCT07558538

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests a single inhaled dose of a lab-made protein (Rh-KGF-2) in 24 adults with moderate to severe ARDS who are on ventilators. The goal is to see if the drug is safe and tolerable, and to find the right dose. Participants are split into three dose groups, with most getting the drug and a few receiving standard care alone. The study lasts 28 days and tracks side effects, oxygen levels, and lung recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

recombinant human keratinocyte growth factor-2 (Rh-KGF-2) inhaled powder

What this could lead to

If it works, this could point toward a new treatment to help repair lung damage in ARDS patients on ventilators.

What could go wrong

This is a very early, small trial (24 people) testing only a single dose. It primarily checks safety, not effectiveness, and the drug may cause airway spasms or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lung injury acute respiratory distress syndrome follicular lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ShanghaiZhongshan

    RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••