Can lung imaging guide ventilator settings to save lives in ARDS?
NCT ID NCT06990477
First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study tests whether using a lung imaging tool called EIT to set ventilator pressure (PEEP) can improve survival in patients with moderate-to-severe ARDS. The trial will enroll 2400 adults and compare EIT-guided PEEP to the standard method. The main goal is to see if this approach reduces deaths within 28 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- EIT-guided PEEP (a device-based method to set ventilator pressure using electrical impedance tomography)
- What this could lead to
- If successful, this could become a standard way to set ventilator pressure for ARDS patients, potentially reducing deaths.
- What could go wrong
- This is a large trial, but the approach is still experimental. It may not improve survival compared to current methods, and individual responses can vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Beijing Chaoyang Hospital of Capital Medical University
NOT_YET_RECRUITINGBeijing, China
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Asan Medical Center
NOT_YET_RECRUITINGSeoul, South Korea
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Department of Critical Care Medicine, Renji Hospital
NOT_YET_RECRUITINGShanghai, China Mainland, 20000, China
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Department of Critical Care Medicine, Zhongshan Hospital of Fudan University
RECRUITINGShanghai, China Mainland, 200000, China
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First Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITINGXian, Shanxi, China
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People's Hospital of Quzhou
NOT_YET_RECRUITINGQuzhou, Zhejiang, China
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Qinghai University Affiliated Hospital
NOT_YET_RECRUITINGXining, Qinghai, China
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Ruijin Hospital Shanghai Jiaotong University School Of Medicine
NOT_YET_RECRUITINGShanghai, China
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Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine
NOT_YET_RECRUITINGHangzhou, China
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Second Hospital of Anhui Medical University
NOT_YET_RECRUITINGHefei, Anhui, China
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Taichung Veterans General Hospital
NOT_YET_RECRUITINGTaichung, Taiwan
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The Affiliated Hospital of Hangzhou Normal University
NOT_YET_RECRUITINGHangzhou, Jiangsu, 210009, China
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The Affiliated Hospital of Xuzhou Medical University
NOT_YET_RECRUITINGXuzhou, Jiangsu, 210009, China
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The First Affiliated Hospital of Guangzhou Medical University
NOT_YET_RECRUITINGGuangzhou, Guangdong, China
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The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, China
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Zhengzhou Central Hospital Affiliated to Zhengzhou University
NOT_YET_RECRUITINGZhengzhou, Henan, China
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Zhongda Hospital, School of Medicine, Southeast University
RECRUITINGNanjing, Jiangsu, 210009, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Immune cell infusion aims to free ARDS patients from ventilators
- New ventilation strategy aims to reduce lung damage in severe pneumonia
- Scientists build a biobank to decode ARDS and personalize treatment
- Scientists hunt for hidden ARDS subtypes to crack deadly lung failure
- Simple chest squeeze may replace High-Tech ventilator settings
- Lab study hopes to unlock ARDS treatment using patient blood cells