Could everyday supplements shield your lungs?

NCT ID NCT01728571

Ongoing Prevention Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial is testing whether taking daily vitamin D3 and fish oil supplements can reduce the risk of lung problems like COPD flare-ups, asthma attacks, and pneumonia in older adults. It involves over 25,000 men and women aged 50 and older who do not have a history of cancer or heart disease. The study also looks at whether these supplements can improve lung function and asthma control. The goal is to see if these simple, over-the-counter supplements could be a practical way to support respiratory health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol) and fish oil (omega-3 fatty acids)
What this could lead to: If effective, these common supplements could offer a simple, low-cost way to reduce respiratory problems like COPD flare-ups, asthma attacks, and pneumonia in older adults.
What could go wrong: This is a large but early-stage analysis; supplements may not show a clear benefit, and results may not apply to everyone. High doses of vitamin D or fish oil can have side effects, though they are generally safe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

asthma chronic obstructive pulmonary disease COPD, severe early onset pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA COPD PNEUMONIA PULMONARY FUNCTION

Contacts and locations

Locations

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

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