Which brace works best? new study tests early vs. late treatment for Kids' overbite

NCT ID NCT07404696

Not yet recruiting Disease control Sponsor: Vastra Gotaland Region Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will enroll 144 children aged 9-13 with a class II malocclusion (overjet of 6 mm or more) to compare three early orthodontic appliances (headgear-activator, twin block, and Invisalign mandibular advancement) against a control group that receives later fixed braces. Researchers will measure how much the overjet improves, how children feel about their teeth and treatment, and the cost-effectiveness of each approach. The goal is to determine if early interceptive treatment is effective and which method is best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: orthodontic appliances (headgear-activator, twin block, Invisalign mandibular advancement, fixed appliance)
What this could lead to: If successful, this could show which early orthodontic treatment works best for correcting overjet and improving quality of life in children, potentially guiding standard care.
What could go wrong: This is a relatively small, early-stage trial (144 participants) comparing different devices, so results may not apply broadly. There is also a risk that no single appliance proves clearly superior.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth Malocclusion, Angle Class II Overbite

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLASS II MALOCCLUSION CLASS II MALOCCLUSION, DIVISION 1 OVERJET

Contacts and locations

Locations

Orthodontic Specialist Clinic

Halmstad, 30246, Sweden
Orthodontic Specialist Clinic

Kungsbacka, 43441, Sweden
Sahlgrenska Academy

Gothenburg, 40530, Sweden

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