Which brace works best? new study tests early vs. late treatment for Kids' overbite
NCT ID NCT07404696
First seen Feb 14, 2026 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This study will enroll 144 children aged 9-13 with a class II malocclusion (overjet of 6 mm or more) to compare three early orthodontic appliances (headgear-activator, twin block, and Invisalign mandibular advancement) against a control group that receives later fixed braces. Researchers will measure how much the overjet improves, how children feel about their teeth and treatment, and the cost-effectiveness of each approach. The goal is to determine if early interceptive treatment is effective and which method is best.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Orthodontic Specialist Clinic
Halmstad, 30246, Sweden
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Orthodontic Specialist Clinic
Kungsbacka, 43441, Sweden
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Sahlgrenska Academy
Gothenburg, 40530, Sweden
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
orthodontic appliances (headgear-activator, twin block, Invisalign mandibular advancement, fixed appliance)
What this could lead to
If successful, this could show which early orthodontic treatment works best for correcting overjet and improving quality of life in children, potentially guiding standard care.
What could go wrong
This is a relatively small, early-stage trial (144 participants) comparing different devices, so results may not apply broadly. There is also a risk that no single appliance proves clearly superior.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.