Malocclusion due to protuberant upper front teeth

This trial compares two approaches to premolar extraction during braces treatment: removing teeth early (before or within a week of getting braces) versus later (after teeth are aligned, just before closing gaps). The goal is to see if extraction timing affects how quickly the fr…

This study tests SureSmile clear aligners in 90 adults with crooked teeth (malocclusion). It compares three different aligner edge designs to see which moves teeth most accurately. Participants wear the aligners as usual, and researchers measure tooth movement against predictions…

This trial investigates whether adding low-intensity pulsed ultrasound to standard twin-block braces can improve jaw joint growth in teenagers with a receding lower jaw (skeletal class II malocclusion). The study involves 24 participants who will receive the combined treatment. T…

This study tests two different spots to place mini implants in the jaw to help pull front teeth back in people with an overbite. Thirty adults with Class II Division 1 malocclusion will get either implants at the cheekbone crest or between tooth roots. The goal is to see which me…

This study tests whether an upper jaw expansion device can encourage the lower jaw to grow forward in children aged 9-11 with an overbite. Sixty participants will receive either an active or non-active Wilson quadhelex appliance for 9 months. Jaw growth is measured with special X…

This study tests a new clear-plate version of the Twin-Block brace against the traditional metal one for children aged 10.5-13 with a receding lower jaw and overbite. The goal is to see if the clear plates work as well at correcting jaw position and bite. Thirty-two participants …

This study tests whether clear aligners with rubber bands can correct a mild overbite (Class II malocclusion) as well as traditional braces. Twenty-four people aged 15-20 will be randomly assigned to either clear aligners or braces, both with elastics. Researchers will measure ch…

This study looks at a small wire called a laceback used with braces. It checks if the laceback affects how clean teeth stay, how often wires break, and how much pain people feel. About 38 people getting braces will have one side of their mouth get the laceback and the other side …

This study tests a new orthodontic system called I-arch to see if it straightens moderately crooked teeth faster and with less discomfort than standard braces. About 34 people aged 12 and older with mild to moderate crowding will take part. Researchers will measure alignment spee…

This study tests whether injecting a form of vitamin D into the gums can speed up tooth movement in adults with braces. Thirty adults with crooked front teeth will receive the injection on one side of the mouth and a placebo on the other. The goal is to see if this approach can s…

This study tests whether giving vitamin D3 locally and using a minor surgical technique called corticision can make orthodontic tooth movement faster. Sixteen patients aged 13-20 who need premolar extractions will be followed for 12 weeks. The goal is to see if these methods safe…

This study looks at whether corrective jaw surgery (orthognathic surgery) can improve depressive symptoms and how patients see their own appearance. Researchers will compare questionnaire results from before and six months after surgery in 20 adults with different types of malocc…