Timing tooth extractions could speed up braces treatment

NCT ID NCT07773389

Disease control Sponsor: Shifa College of Dentistry Source: ClinicalTrials.gov ↗

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial compares two approaches to premolar extraction during braces treatment: removing teeth early (before or within a week of getting braces) versus later (after teeth are aligned, just before closing gaps). The goal is to see if extraction timing affects how quickly the front teeth move back to close the gaps. Participants aged 13–25 with Class I or II malocclusion will be randomly assigned to one of the two groups, and their tooth movement will be tracked over six months using 3D scans. The study also looks at gum health, pain, and anxiety related to the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Timing of premolar extraction (early vs late) during fixed orthodontic treatment
What this could lead to: If timing matters, orthodontists could shorten treatment by choosing the best extraction point, reducing discomfort and improving results.
What could go wrong: This is a small, early-stage trial, so results may not apply to everyone. Extraction timing may not significantly change tooth movement, and individual responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 26 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2026

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

13 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 13-25 years 2. No prior orthodontic treatment 3. Overjet 4-8 mm 4. Symmetric dental arches with mild to moderate crowding requiring bilateral first premolar extractions. 5. Probing depth less than 4 mm on all teeth Exclusion Criteria: 1. History of dental trauma 2. Poor oral hygiene 3. Syndromic patients 4. Systemic diseases or medications affecting bone metabolism

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth Malocclusion, Angle Class I

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Malocclusion class II Malocclusion, angle class I

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Timing tooth extractions could speed up braces treatment

What the study statuses mean