Malocclusion due to protuberant upper front teeth

This trial tests whether 3D-printed metal retainers (made from cobalt-chromium or titanium) work better than the standard twisted-wire retainer at keeping teeth from shifting after braces. Thirty-six adults who have just finished orthodontic treatment will receive one of the thre…

This study will enroll 144 children aged 9-13 with a class II malocclusion (overjet of 6 mm or more) to compare three early orthodontic appliances (headgear-activator, twin block, and Invisalign mandibular advancement) against a control group that receives later fixed braces. Res…

This trial compares two dental devices—the Twin Block and the Carriere Motion Appliance—for correcting Class II malocclusion (overbite) in teens aged 14.5 to 16. It will measure how well each device moves the teeth and jaw, and how treatment affects daily life and comfort. The go…

Clear aligners straighten teeth with removable plastic trays, but different materials may cause different levels of pain and irritation. This trial compares two common plastics, TPU and PETG, to see which one patients find more comfortable. About 34 people with mild to moderate c…

This study compares two techniques to speed up the movement of upper canine teeth during orthodontic treatment: micro-osteoperforation (creating tiny holes in the jawbone) and photobiomodulation (low-level laser therapy). 75 people needing premolar extractions as part of braces w…

This study tests whether taking a daily vitamin D supplement (1000 IU) for 4 months can reduce pain, speed tooth movement, and improve bone density in people getting braces. Researchers will compare vitamin D to a placebo in 48 adults aged 18-35 with crooked teeth. Participants w…

This study will compare custom 3D printed splints made at the hospital with those made by outside companies for jaw surgery. The splints help surgeons align the teeth and jaws correctly during the operation. Researchers want to see if the in-house splints are faster to get, cheap…

This study looks at how two types of clear aligners—3D-printed versus thermoformed—affect bone metabolism in adults with minor crowding. Thirty participants will be randomly assigned to one type, and researchers will measure changes in a bone-related protein and gum health. The g…

This study uses computer simulations to compare custom-made implants with standard miniplates for fixing the upper jaw after surgery. Researchers will analyze stress on the implants and bone, as well as jaw movement, in two different surgical scenarios. The goal is to provide ins…