Do 3D-printed aligners change bone health differently than standard ones?
NCT ID NCT07617571
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how two types of clear aligners—3D-printed versus thermoformed—affect bone metabolism in adults with minor crowding. Thirty participants will be randomly assigned to one type, and researchers will measure changes in a bone-related protein and gum health. The goal is to see if the manufacturing method makes a difference in how the jawbone responds to tooth movement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Orthodontic aligners (3D-printed resin or thermoformed PETG)
- What this could lead to
- If successful, this could help orthodontists choose aligner materials that are gentler on bone, potentially improving treatment outcomes.
- What could go wrong
- This is a small, early-stage study (30 people) measuring bone markers, not clinical outcomes. Results may not translate to real-world benefits or apply to more complex cases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dentistry, Alexandria University
Alexandria, Egypt
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Other studies related to the condition(s) this trial covers.
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