Do 3D-printed aligners change bone health differently than standard ones?
NCT ID NCT07617571
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how two types of clear aligners—3D-printed versus thermoformed—affect bone metabolism in adults with minor crowding. Thirty participants will be randomly assigned to one type, and researchers will measure changes in a bone-related protein and gum health. The goal is to see if the manufacturing method makes a difference in how the jawbone responds to tooth movement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Orthodontic aligners (3D-printed resin or thermoformed PETG)
What this could lead to
If successful, this could help orthodontists choose aligner materials that are gentler on bone, potentially improving treatment outcomes.
What could go wrong
This is a small, early-stage study (30 people) measuring bone markers, not clinical outcomes. Results may not translate to real-world benefits or apply to more complex cases.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MALOCCLUSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Faculty of Dentistry, Alexandria University
Alexandria, Egypt
Contact
Contact