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Chewing on a silicone gadget may make clear aligners work better — a trial puts it to the test

NCT ID NCT07726485

Symptom relief Sponsor: University of Baghdad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether using a silicone aligner seater (a chewy) more often can improve how well clear aligners move teeth as planned. Adults aged 18 to 45 with mild to moderate crowding or spacing will be randomly assigned to use the chewy only when first inserting each aligner set or also daily at bedtime. The study will compare tooth movement accuracy and pain levels between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silicone aligner seater (chewy) used during clear aligner therapy
What this could lead to
If it works, this could point toward a simple way to make clear aligner treatment more predictable and effective.
What could go wrong
This is a small, early-stage trial with only 34 participants, so results may not apply to everyone. The intervention is low-risk, but the benefit may be minimal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 34 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female participants. * Age between 18 and 45 years. * Mild to moderate crowding or spacing. * ANB angle between 1° and 5°. * Planned for non-extraction clear aligner treatment. * Willing and able to provide written informed consent and comply with the study protocol. Exclusion Criteria: * Craniofacial syndromes (e.g., cleft lip and/or palate) or other congenital craniofacial anomalies. * Severe crowding. * Signs and/or symptoms of temporomandibular disorders (TMD). * Previous orthodontic treatment.

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Conditions

The condition(s) this trial relates to.

Malocclusion malocclusion due to protuberant upper front teeth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clear aligner therapy Malocclusions

Contacts and locations

Locations

  • University of Baghdad/ collage of Dentistry

    Baghdad, 10047, Iraq

More trials for these conditions

Other studies related to the condition(s) this trial covers.