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Jaw surgery may lift depression along with the bite

NCT ID NCT07702448

Knowledge-focused Sponsor: Kırıkkale University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study looks at whether corrective jaw surgery (orthognathic surgery) can improve depressive symptoms and how patients see their own appearance. Researchers will compare questionnaire results from before and six months after surgery in 20 adults with different types of malocclusion. The goal is to understand the psychological benefits beyond the physical correction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bimaxillary orthognathic surgery
What this could lead to
If successful, this study could show that jaw correction surgery improves mental health and quality of life for people with severe bite problems.
What could go wrong
This is a small, observational study with only 20 participants, so results may not apply to everyone. It cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 18 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients aged 18-40 years with different types of malocclusion who are scheduled to undergo bimaxillary orthognathic surgery at the Faculty of Dentistry, Kırıkkale University. Eligible participants will be evaluated 1 week before surgery and 6 months after surgery using validated patient-reported outcome measures assessing depressive symptoms, self-esteem, and orthognathic quality of life.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 40 years. * Individuals without systemic diseases. * Patients with an indication for bimaxillary orthognathic surgery. * Patients who complete the study questionnaires 1 week before surgery and 6 months after surgery. * Individuals who use at least one of the following social media platforms: Instagram, WhatsApp, Snapchat, X, TikTok, or Telegram. * Individuals who provide written informed consent to participate in the study. * Patients scheduled to undergo treatment at the Faculty of Dentistry, Kırıkkale University. Exclusion Criteria: * Patients without an indication for bimaxillary orthognathic surgery or those undergoing single-jaw surgery only. * Individuals with systemic diseases (e.g., diabetes mellitus, hypertension, or thyroid disorders). * Patients with a diagnosed psychiatric disorder. * Patients with a history of previous orthognathic surgery. * Patients scheduled to undergo additional esthetic procedures (e.g., genioplasty, botulinum toxin injection, or dermal filler treatment). * Individuals who decline to participate or do not provide written informed consent.

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Conditions

The condition(s) this trial relates to.

Dentofacial Deformities Malocclusion malocclusion due to protuberant upper front teeth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentofacial deformities Malocclusions Orthognathic surgery

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Kırıkkale University Faculty of Dentistry

    RECRUITING

    Kirikkale, Kırıkkale, 71450, Turkey (Türkiye)

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