Can a tweaked jaw surgery cut nerve damage risk?

NCT ID NCT07746700

Not yet recruiting Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests a modified jaw surgery technique, called low sagittal medial ramus osteotomy, for people with severe bite misalignment (skeletal Class II or III malocclusion). The procedure aims to reposition the jaw with fewer complications than the standard surgery, particularly by reducing the chance of nerve injury and unwanted bone fractures. Researchers will evaluate outcomes in 11 healthy adults aged 18 to 45, measuring both surgical success and nerve function recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Low sagittal medial ramus osteotomy, a modified surgical procedure for jaw repositioning
What this could lead to: If successful, this modified jaw surgery could offer a safer way to correct severe bite misalignment, with fewer nerve injuries and fewer surgical complications.
What could go wrong: This is a small, early-stage trial with only 11 participants, so results may not apply broadly. Surgery carries inherent risks like infection, bleeding, or nerve damage, and the modified technique may not prove safer than the standard approach.

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Conditions

The condition(s) this trial relates to.

autosomal dominant prognathism Dentofacial Deformities

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTOFACIAL DEFORMITIES SKELETAL CLASS II MALOCCLUSION SKELETAL CLASS III MALOCCLUSION

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